AustralieFrV1, Main, Exploration, bibRecord, 002E00

Feasibility and Domain Validation of RA Flare Core Domain Set: A Report of the OMERACT 2014 RA Flare Group Plenary

Identifieur interne : 002E00 ( Main/Exploration ); précédent : 002D99; suivant : 002E01

Feasibility and Domain Validation of RA Flare Core Domain Set: A Report of the OMERACT 2014 RA Flare Group Plenary

Auteurs : Susan J. Bartlett [États-Unis] ; Vivian P. Bykerk [États-Unis] ; Roxanne Cooksey [Royaume-Uni] ; Ernest H. Choy [Royaume-Uni] ; Rieke Alten [Allemagne] ; Robin Christensen [Danemark] ; Daniel E. Furst [États-Unis] ; Francis Guillemin [France] ; Serena Halls [Royaume-Uni] ; Sarah Hewlett [Royaume-Uni] ; Amye L. Leong [États-Unis] ; Anne Lyddiatt ; Lyn March [Australie] ; Pamela Montie ; Ana Maria Orbai ; Christoph Pohl [Allemagne] ; Marieke Scholte Voshaar [Pays-Bas] ; Thasia G. Woodworth [États-Unis] ; Clifton O. Bingham

Source :

The Journal of rheumatology [ 0315-162X ] ; 2015.

RBID : PMC:4747421

Descripteurs français

English descriptors

KwdEn :
- Arthritis, Rheumatoid (physiopathology), Consensus Development Conferences as Topic, Disease Progression, Feasibility Studies, Female, Humans, Male, Observational Studies as Topic, Outcome Assessment (Health Care), Pain Measurement, Quebec, Randomized Controlled Trials as Topic.
MESH :
- geographic : Quebec.
- physiopathology : Arthritis, Rheumatoid.
- Consensus Development Conferences as Topic, Disease Progression, Feasibility Studies, Female, Humans, Male, Observational Studies as Topic, Outcome Assessment (Health Care), Pain Measurement, Randomized Controlled Trials as Topic.

Abstract

Objective

The OMERACT RA Flare Group was established to develop an approach to identify and measure rheumatoid arthritis (RA) flares. Here, we provide an overview of our OMERACT 2014 plenary.

Methods

Feasibility and validity of flare domains endorsed at OMERACT 11 (2012) were described based on initial data from three international studies collected using a common set of questions specific to RA flare. Mean flare frequency, severity, and duration data were presented, and domain scores were compared by flare status to examine known-groups validity. Breakout groups provided input for stiffness, self-management, contextual factors, and measurement considerations.

Results

Flare data from 501 patients in a observational study indicated 39% were in a flare, with mean (SD) severity of 6.0 (2.6) and 55% lasting > 14 days. Pain, physical function, fatigue, participation and stiffness scores averaged ≥ 2 times higher (2 of 11 points) in flaring individuals. Correlations between flare domains and corresponding legacy instruments were r’s from 0.46 to 0.93. A combined definition (patient-report of flare and DAS28 increase) was evaluated in two other trials with similar results. Breakout groups debated specific measurement issues.

Conclusion

These data contribute initial evidence of feasibility and content validation of the OMERACT RA Flare Core Domain Set. Our research agenda for OMERACT 2016 includes establishing duration/intensity criteria and developing criteria to identify RA flares using existing disease activity measures. Ongoing work will also address discordance between patients and physician ratings, facilitate applications to clinical care, elucidate the role of self-management and help finalize recommendations for RA flare measurement.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747421

DOI: 10.3899/jrheum.141169
PubMed: 25684764
PubMed Central: 4747421

Affiliations:

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Feasibility and Domain Validation of RA Flare Core Domain Set: A Report of the OMERACT 2014 RA Flare Group Plenary</title>
<author><name sortKey="Bartlett, Susan J" sort="Bartlett, Susan J" uniqKey="Bartlett S" first="Susan J." last="Bartlett">Susan J. Bartlett</name>
<affiliation wicri:level="2"><nlm:aff id="A1">McGill University, Montreal, CA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>McGill University, Montreal</wicri:cityArea>
</affiliation>
<affiliation><nlm:aff id="A2">Johns Hopkins University, Baltimore USA</nlm:aff>
<wicri:noCountry code="subfield">Baltimore USA</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Bykerk, Vivian P" sort="Bykerk, Vivian P" uniqKey="Bykerk V" first="Vivian P." last="Bykerk">Vivian P. Bykerk</name>
<affiliation wicri:level="2"><nlm:aff id="A3">Hospital for Special Surgery, New York, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Hospital for Special Surgery, New York</wicri:regionArea>
<placeName><region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Cooksey, Roxanne" sort="Cooksey, Roxanne" uniqKey="Cooksey R" first="Roxanne" last="Cooksey">Roxanne Cooksey</name>
<affiliation wicri:level="1"><nlm:aff id="A4">Swansea University, Swansea, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Swansea University, Swansea</wicri:regionArea>
<wicri:noRegion>Swansea</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Choy, Ernest H" sort="Choy, Ernest H" uniqKey="Choy E" first="Ernest H." last="Choy">Ernest H. Choy</name>
<affiliation wicri:level="1"><nlm:aff id="A5">Cardiff University, Cardiff, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Cardiff University, Cardiff</wicri:regionArea>
<wicri:noRegion>Cardiff</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Alten, Rieke" sort="Alten, Rieke" uniqKey="Alten R" first="Rieke" last="Alten">Rieke Alten</name>
<affiliation wicri:level="1"><nlm:aff id="A6">Schlosspark-Klinik, University Medicine Berlin, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Schlosspark-Klinik, University Medicine Berlin</wicri:regionArea>
<wicri:noRegion>University Medicine Berlin</wicri:noRegion>
<wicri:noRegion>University Medicine Berlin</wicri:noRegion>
<wicri:noRegion>University Medicine Berlin</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Christensen, Robin" sort="Christensen, Robin" uniqKey="Christensen R" first="Robin" last="Christensen">Robin Christensen</name>
<affiliation wicri:level="1"><nlm:aff id="A7">The Parker Institute, Copenhagen University Hospital at Frederiksberg, Copenhagen F, Denmark</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea>The Parker Institute, Copenhagen University Hospital at Frederiksberg, Copenhagen F</wicri:regionArea>
<wicri:noRegion>Copenhagen F</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Furst, Daniel E" sort="Furst, Daniel E" uniqKey="Furst D" first="Daniel E." last="Furst">Daniel E. Furst</name>
<affiliation wicri:level="3"><nlm:aff id="A8">University of California, Los Angeles, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>University of California, Los Angeles</wicri:regionArea>
<placeName><settlement type="city">Los Angeles</settlement>
<region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Guillemin, Francis" sort="Guillemin, Francis" uniqKey="Guillemin F" first="Francis" last="Guillemin">Francis Guillemin</name>
<affiliation wicri:level="3"><nlm:aff id="A9">University of Lorraine, Nancy, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>University of Lorraine, Nancy</wicri:regionArea>
<placeName><region type="region">Grand Est</region>
<region type="old region">Lorraine (région)</region>
<settlement type="city">Nancy</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Halls, Serena" sort="Halls, Serena" uniqKey="Halls S" first="Serena" last="Halls">Serena Halls</name>
<affiliation wicri:level="1"><nlm:aff id="A10">University of the West of England, Bristol, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>University of the West of England, Bristol</wicri:regionArea>
<wicri:noRegion>Bristol</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Hewlett, Sarah" sort="Hewlett, Sarah" uniqKey="Hewlett S" first="Sarah" last="Hewlett">Sarah Hewlett</name>
<affiliation wicri:level="1"><nlm:aff id="A10">University of the West of England, Bristol, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>University of the West of England, Bristol</wicri:regionArea>
<wicri:noRegion>Bristol</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Leong, Amye L" sort="Leong, Amye L" uniqKey="Leong A" first="Amye L." last="Leong">Amye L. Leong</name>
<affiliation wicri:level="1"><nlm:aff id="A11">Healthy Motivation, Santa Barbara, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Healthy Motivation, Santa Barbara</wicri:regionArea>
<wicri:noRegion>Santa Barbara</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Lyddiatt, Anne" sort="Lyddiatt, Anne" uniqKey="Lyddiatt A" first="Anne" last="Lyddiatt">Anne Lyddiatt</name>
</author>
<author><name sortKey="March, Lyn" sort="March, Lyn" uniqKey="March L" first="Lyn" last="March">Lyn March</name>
<affiliation wicri:level="1"><nlm:aff id="A12">University of Sydney, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>University of Sydney</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Montie, Pamela" sort="Montie, Pamela" uniqKey="Montie P" first="Pamela" last="Montie">Pamela Montie</name>
</author>
<author><name sortKey="Orbai, Ana Maria" sort="Orbai, Ana Maria" uniqKey="Orbai A" first="Ana Maria" last="Orbai">Ana Maria Orbai</name>
<affiliation><nlm:aff id="A2">Johns Hopkins University, Baltimore USA</nlm:aff>
<wicri:noCountry code="subfield">Baltimore USA</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Pohl, Christoph" sort="Pohl, Christoph" uniqKey="Pohl C" first="Christoph" last="Pohl">Christoph Pohl</name>
<affiliation wicri:level="1"><nlm:aff id="A6">Schlosspark-Klinik, University Medicine Berlin, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Schlosspark-Klinik, University Medicine Berlin</wicri:regionArea>
<wicri:noRegion>University Medicine Berlin</wicri:noRegion>
<wicri:noRegion>University Medicine Berlin</wicri:noRegion>
<wicri:noRegion>University Medicine Berlin</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Voshaar, Marieke Scholte" sort="Voshaar, Marieke Scholte" uniqKey="Voshaar M" first="Marieke Scholte" last="Voshaar">Marieke Scholte Voshaar</name>
<affiliation wicri:level="4"><nlm:aff id="A13">University of Twente, Enschede, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>University of Twente, Enschede</wicri:regionArea>
<orgName type="university">Université de Twente</orgName>
<placeName><settlement type="city">Enschede</settlement>
<region nuts="2">Overijssel</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Woodworth, Thasia G" sort="Woodworth, Thasia G" uniqKey="Woodworth T" first="Thasia G." last="Woodworth">Thasia G. Woodworth</name>
<affiliation wicri:level="3"><nlm:aff id="A8">University of California, Los Angeles, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>University of California, Los Angeles</wicri:regionArea>
<placeName><settlement type="city">Los Angeles</settlement>
<region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Bingham, Clifton O" sort="Bingham, Clifton O" uniqKey="Bingham C" first="Clifton O." last="Bingham">Clifton O. Bingham</name>
<affiliation><nlm:aff id="A2">Johns Hopkins University, Baltimore USA</nlm:aff>
<wicri:noCountry code="subfield">Baltimore USA</wicri:noCountry>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">25684764</idno>
<idno type="pmc">4747421</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747421</idno>
<idno type="RBID">PMC:4747421</idno>
<idno type="doi">10.3899/jrheum.141169</idno>
<date when="2015">2015</date>
<idno type="wicri:Area/Pmc/Corpus">001F46</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001F46</idno>
<idno type="wicri:Area/Pmc/Curation">001E00</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001E00</idno>
<idno type="wicri:Area/Pmc/Checkpoint">001006</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">001006</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="wicri:Area/PubMed/Corpus">002745</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002745</idno>
<idno type="wicri:Area/PubMed/Curation">002676</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002676</idno>
<idno type="wicri:Area/PubMed/Checkpoint">002676</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">002676</idno>
<idno type="wicri:Area/Ncbi/Merge">002261</idno>
<idno type="wicri:Area/Ncbi/Curation">002261</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">002261</idno>
<idno type="wicri:doubleKey">0315-162X:2015:Bartlett S:feasibility:and:domain</idno>
<idno type="wicri:Area/Main/Merge">002E01</idno>
<idno type="wicri:Area/Main/Curation">002E00</idno>
<idno type="wicri:Area/Main/Exploration">002E00</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Feasibility and Domain Validation of RA Flare Core Domain Set: A Report of the OMERACT 2014 RA Flare Group Plenary</title>
<author><name sortKey="Bartlett, Susan J" sort="Bartlett, Susan J" uniqKey="Bartlett S" first="Susan J." last="Bartlett">Susan J. Bartlett</name>
<affiliation wicri:level="2"><nlm:aff id="A1">McGill University, Montreal, CA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>McGill University, Montreal</wicri:cityArea>
</affiliation>
<affiliation><nlm:aff id="A2">Johns Hopkins University, Baltimore USA</nlm:aff>
<wicri:noCountry code="subfield">Baltimore USA</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Bykerk, Vivian P" sort="Bykerk, Vivian P" uniqKey="Bykerk V" first="Vivian P." last="Bykerk">Vivian P. Bykerk</name>
<affiliation wicri:level="2"><nlm:aff id="A3">Hospital for Special Surgery, New York, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Hospital for Special Surgery, New York</wicri:regionArea>
<placeName><region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Cooksey, Roxanne" sort="Cooksey, Roxanne" uniqKey="Cooksey R" first="Roxanne" last="Cooksey">Roxanne Cooksey</name>
<affiliation wicri:level="1"><nlm:aff id="A4">Swansea University, Swansea, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Swansea University, Swansea</wicri:regionArea>
<wicri:noRegion>Swansea</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Choy, Ernest H" sort="Choy, Ernest H" uniqKey="Choy E" first="Ernest H." last="Choy">Ernest H. Choy</name>
<affiliation wicri:level="1"><nlm:aff id="A5">Cardiff University, Cardiff, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Cardiff University, Cardiff</wicri:regionArea>
<wicri:noRegion>Cardiff</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Alten, Rieke" sort="Alten, Rieke" uniqKey="Alten R" first="Rieke" last="Alten">Rieke Alten</name>
<affiliation wicri:level="1"><nlm:aff id="A6">Schlosspark-Klinik, University Medicine Berlin, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Schlosspark-Klinik, University Medicine Berlin</wicri:regionArea>
<wicri:noRegion>University Medicine Berlin</wicri:noRegion>
<wicri:noRegion>University Medicine Berlin</wicri:noRegion>
<wicri:noRegion>University Medicine Berlin</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Christensen, Robin" sort="Christensen, Robin" uniqKey="Christensen R" first="Robin" last="Christensen">Robin Christensen</name>
<affiliation wicri:level="1"><nlm:aff id="A7">The Parker Institute, Copenhagen University Hospital at Frederiksberg, Copenhagen F, Denmark</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea>The Parker Institute, Copenhagen University Hospital at Frederiksberg, Copenhagen F</wicri:regionArea>
<wicri:noRegion>Copenhagen F</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Furst, Daniel E" sort="Furst, Daniel E" uniqKey="Furst D" first="Daniel E." last="Furst">Daniel E. Furst</name>
<affiliation wicri:level="3"><nlm:aff id="A8">University of California, Los Angeles, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>University of California, Los Angeles</wicri:regionArea>
<placeName><settlement type="city">Los Angeles</settlement>
<region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Guillemin, Francis" sort="Guillemin, Francis" uniqKey="Guillemin F" first="Francis" last="Guillemin">Francis Guillemin</name>
<affiliation wicri:level="3"><nlm:aff id="A9">University of Lorraine, Nancy, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>University of Lorraine, Nancy</wicri:regionArea>
<placeName><region type="region">Grand Est</region>
<region type="old region">Lorraine (région)</region>
<settlement type="city">Nancy</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Halls, Serena" sort="Halls, Serena" uniqKey="Halls S" first="Serena" last="Halls">Serena Halls</name>
<affiliation wicri:level="1"><nlm:aff id="A10">University of the West of England, Bristol, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>University of the West of England, Bristol</wicri:regionArea>
<wicri:noRegion>Bristol</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Hewlett, Sarah" sort="Hewlett, Sarah" uniqKey="Hewlett S" first="Sarah" last="Hewlett">Sarah Hewlett</name>
<affiliation wicri:level="1"><nlm:aff id="A10">University of the West of England, Bristol, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>University of the West of England, Bristol</wicri:regionArea>
<wicri:noRegion>Bristol</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Leong, Amye L" sort="Leong, Amye L" uniqKey="Leong A" first="Amye L." last="Leong">Amye L. Leong</name>
<affiliation wicri:level="1"><nlm:aff id="A11">Healthy Motivation, Santa Barbara, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Healthy Motivation, Santa Barbara</wicri:regionArea>
<wicri:noRegion>Santa Barbara</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Lyddiatt, Anne" sort="Lyddiatt, Anne" uniqKey="Lyddiatt A" first="Anne" last="Lyddiatt">Anne Lyddiatt</name>
</author>
<author><name sortKey="March, Lyn" sort="March, Lyn" uniqKey="March L" first="Lyn" last="March">Lyn March</name>
<affiliation wicri:level="1"><nlm:aff id="A12">University of Sydney, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>University of Sydney</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Montie, Pamela" sort="Montie, Pamela" uniqKey="Montie P" first="Pamela" last="Montie">Pamela Montie</name>
</author>
<author><name sortKey="Orbai, Ana Maria" sort="Orbai, Ana Maria" uniqKey="Orbai A" first="Ana Maria" last="Orbai">Ana Maria Orbai</name>
<affiliation><nlm:aff id="A2">Johns Hopkins University, Baltimore USA</nlm:aff>
<wicri:noCountry code="subfield">Baltimore USA</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Pohl, Christoph" sort="Pohl, Christoph" uniqKey="Pohl C" first="Christoph" last="Pohl">Christoph Pohl</name>
<affiliation wicri:level="1"><nlm:aff id="A6">Schlosspark-Klinik, University Medicine Berlin, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Schlosspark-Klinik, University Medicine Berlin</wicri:regionArea>
<wicri:noRegion>University Medicine Berlin</wicri:noRegion>
<wicri:noRegion>University Medicine Berlin</wicri:noRegion>
<wicri:noRegion>University Medicine Berlin</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Voshaar, Marieke Scholte" sort="Voshaar, Marieke Scholte" uniqKey="Voshaar M" first="Marieke Scholte" last="Voshaar">Marieke Scholte Voshaar</name>
<affiliation wicri:level="4"><nlm:aff id="A13">University of Twente, Enschede, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>University of Twente, Enschede</wicri:regionArea>
<orgName type="university">Université de Twente</orgName>
<placeName><settlement type="city">Enschede</settlement>
<region nuts="2">Overijssel</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Woodworth, Thasia G" sort="Woodworth, Thasia G" uniqKey="Woodworth T" first="Thasia G." last="Woodworth">Thasia G. Woodworth</name>
<affiliation wicri:level="3"><nlm:aff id="A8">University of California, Los Angeles, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>University of California, Los Angeles</wicri:regionArea>
<placeName><settlement type="city">Los Angeles</settlement>
<region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Bingham, Clifton O" sort="Bingham, Clifton O" uniqKey="Bingham C" first="Clifton O." last="Bingham">Clifton O. Bingham</name>
<affiliation><nlm:aff id="A2">Johns Hopkins University, Baltimore USA</nlm:aff>
<wicri:noCountry code="subfield">Baltimore USA</wicri:noCountry>
</affiliation>
</author>
</analytic>
<series><title level="j">The Journal of rheumatology</title>
<idno type="ISSN">0315-162X</idno>
<imprint><date when="2015">2015</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Arthritis, Rheumatoid (physiopathology)</term>
<term>Consensus Development Conferences as Topic</term>
<term>Disease Progression</term>
<term>Feasibility Studies</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Observational Studies as Topic</term>
<term>Outcome Assessment (Health Care)</term>
<term>Pain Measurement</term>
<term>Quebec</term>
<term>Randomized Controlled Trials as Topic</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Conférences de consensus comme sujet</term>
<term>Essais contrôlés randomisés comme sujet</term>
<term>Femelle</term>
<term>Humains</term>
<term>Mesure de la douleur</term>
<term>Mâle</term>
<term>Polyarthrite rhumatoïde (physiopathologie)</term>
<term>Québec</term>
<term>Étude d'observation comme sujet</term>
<term>Études de faisabilité</term>
<term>Évaluation de résultat (soins)</term>
<term>Évolution de la maladie</term>
</keywords>
<keywords scheme="MESH" type="geographic" xml:lang="en"><term>Quebec</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathologie" xml:lang="fr"><term>Polyarthrite rhumatoïde</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Arthritis, Rheumatoid</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Consensus Development Conferences as Topic</term>
<term>Disease Progression</term>
<term>Feasibility Studies</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Observational Studies as Topic</term>
<term>Outcome Assessment (Health Care)</term>
<term>Pain Measurement</term>
<term>Randomized Controlled Trials as Topic</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Conférences de consensus comme sujet</term>
<term>Essais contrôlés randomisés comme sujet</term>
<term>Femelle</term>
<term>Humains</term>
<term>Mesure de la douleur</term>
<term>Mâle</term>
<term>Québec</term>
<term>Étude d'observation comme sujet</term>
<term>Études de faisabilité</term>
<term>Évaluation de résultat (soins)</term>
<term>Évolution de la maladie</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><sec id="S1"><title>Objective</title>
<p id="P1">The OMERACT RA Flare Group was established to develop an approach to identify and measure rheumatoid arthritis (RA) flares. Here, we provide an overview of our OMERACT 2014 plenary.</p>
</sec>
<sec id="S2"><title>Methods</title>
<p id="P2">Feasibility and validity of flare domains endorsed at OMERACT 11 (2012) were described based on initial data from three international studies collected using a common set of questions specific to RA flare. Mean flare frequency, severity, and duration data were presented, and domain scores were compared by flare status to examine known-groups validity. Breakout groups provided input for stiffness, self-management, contextual factors, and measurement considerations.</p>
</sec>
<sec id="S3"><title>Results</title>
<p id="P3">Flare data from 501 patients in a observational study indicated 39% were in a flare, with mean (SD) severity of 6.0 (2.6) and 55% lasting > 14 days. Pain, physical function, fatigue, participation and stiffness scores averaged ≥ 2 times higher (2 of 11 points) in flaring individuals. Correlations between flare domains and corresponding legacy instruments were r’s from 0.46 to 0.93. A combined definition (patient-report of flare and DAS28 increase) was evaluated in two other trials with similar results. Breakout groups debated specific measurement issues.</p>
</sec>
<sec id="S4"><title>Conclusion</title>
<p id="P4">These data contribute initial evidence of feasibility and content validation of the OMERACT RA Flare Core Domain Set. Our research agenda for OMERACT 2016 includes establishing duration/intensity criteria and developing criteria to identify RA flares using existing disease activity measures. Ongoing work will also address discordance between patients and physician ratings, facilitate applications to clinical care, elucidate the role of self-management and help finalize recommendations for RA flare measurement.</p>
</sec>
</div>
</front>
</TEI>
<affiliations><list><country><li>Allemagne</li>
<li>Australie</li>
<li>Danemark</li>
<li>France</li>
<li>Pays-Bas</li>
<li>Royaume-Uni</li>
<li>États-Unis</li>
</country>
<region><li>Californie</li>
<li>Grand Est</li>
<li>Lorraine (région)</li>
<li>Overijssel</li>
<li>État de New York</li>
</region>
<settlement><li>Enschede</li>
<li>Los Angeles</li>
<li>Nancy</li>
</settlement>
<orgName><li>Université de Twente</li>
</orgName>
</list>
<tree><noCountry><name sortKey="Bingham, Clifton O" sort="Bingham, Clifton O" uniqKey="Bingham C" first="Clifton O." last="Bingham">Clifton O. Bingham</name>
<name sortKey="Lyddiatt, Anne" sort="Lyddiatt, Anne" uniqKey="Lyddiatt A" first="Anne" last="Lyddiatt">Anne Lyddiatt</name>
<name sortKey="Montie, Pamela" sort="Montie, Pamela" uniqKey="Montie P" first="Pamela" last="Montie">Pamela Montie</name>
<name sortKey="Orbai, Ana Maria" sort="Orbai, Ana Maria" uniqKey="Orbai A" first="Ana Maria" last="Orbai">Ana Maria Orbai</name>
</noCountry>
<country name="États-Unis"><region name="Californie"><name sortKey="Bartlett, Susan J" sort="Bartlett, Susan J" uniqKey="Bartlett S" first="Susan J." last="Bartlett">Susan J. Bartlett</name>
</region>
<name sortKey="Bykerk, Vivian P" sort="Bykerk, Vivian P" uniqKey="Bykerk V" first="Vivian P." last="Bykerk">Vivian P. Bykerk</name>
<name sortKey="Furst, Daniel E" sort="Furst, Daniel E" uniqKey="Furst D" first="Daniel E." last="Furst">Daniel E. Furst</name>
<name sortKey="Leong, Amye L" sort="Leong, Amye L" uniqKey="Leong A" first="Amye L." last="Leong">Amye L. Leong</name>
<name sortKey="Woodworth, Thasia G" sort="Woodworth, Thasia G" uniqKey="Woodworth T" first="Thasia G." last="Woodworth">Thasia G. Woodworth</name>
</country>
<country name="Royaume-Uni"><noRegion><name sortKey="Cooksey, Roxanne" sort="Cooksey, Roxanne" uniqKey="Cooksey R" first="Roxanne" last="Cooksey">Roxanne Cooksey</name>
</noRegion>
<name sortKey="Choy, Ernest H" sort="Choy, Ernest H" uniqKey="Choy E" first="Ernest H." last="Choy">Ernest H. Choy</name>
<name sortKey="Halls, Serena" sort="Halls, Serena" uniqKey="Halls S" first="Serena" last="Halls">Serena Halls</name>
<name sortKey="Hewlett, Sarah" sort="Hewlett, Sarah" uniqKey="Hewlett S" first="Sarah" last="Hewlett">Sarah Hewlett</name>
</country>
<country name="Allemagne"><noRegion><name sortKey="Alten, Rieke" sort="Alten, Rieke" uniqKey="Alten R" first="Rieke" last="Alten">Rieke Alten</name>
</noRegion>
<name sortKey="Pohl, Christoph" sort="Pohl, Christoph" uniqKey="Pohl C" first="Christoph" last="Pohl">Christoph Pohl</name>
</country>
<country name="Danemark"><noRegion><name sortKey="Christensen, Robin" sort="Christensen, Robin" uniqKey="Christensen R" first="Robin" last="Christensen">Robin Christensen</name>
</noRegion>
</country>
<country name="France"><region name="Grand Est"><name sortKey="Guillemin, Francis" sort="Guillemin, Francis" uniqKey="Guillemin F" first="Francis" last="Guillemin">Francis Guillemin</name>
</region>
</country>
<country name="Australie"><noRegion><name sortKey="March, Lyn" sort="March, Lyn" uniqKey="March L" first="Lyn" last="March">Lyn March</name>
</noRegion>
</country>
<country name="Pays-Bas"><region name="Overijssel"><name sortKey="Voshaar, Marieke Scholte" sort="Voshaar, Marieke Scholte" uniqKey="Voshaar M" first="Marieke Scholte" last="Voshaar">Marieke Scholte Voshaar</name>
</region>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002E00 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 002E00 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Asie
   |area=    AustralieFrV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     PMC:4747421
   |texte=   Feasibility and Domain Validation of RA Flare Core Domain Set: A Report of the OMERACT 2014 RA Flare Group Plenary
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:25684764" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a AustralieFrV1

This area was generated with Dilib version V0.6.33.
Data generation: Tue Dec 5 10:43:12 2017. Site generation: Tue Mar 5 14:07:20 2024

Serveur d'exploration sur les relations entre la France et l'Australie

Feasibility and Domain Validation of RA Flare Core Domain Set: A Report of the OMERACT 2014 RA Flare Group Plenary

Feasibility and Domain Validation of RA Flare Core Domain Set: A Report of the OMERACT 2014 RA Flare Group Plenary

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration sur les relations entre la France et l'Australie
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.